3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester

3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester - Names and Identifiers

Name	3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester
Synonyms	AKOS BC-0708 BUTTPARK 1009-33 AKOS BBS-00002579 5-AMINO-1H-PYRAZOLE-4-CARBOXYLIC ETHYL 5-AMINOPYRAZOLE-4-CARBOXYLATE Ethyl-5-amino-1H-pyrazol-4-carboxylat Ethyl 5-Amino-1H-4-Pyrazolecarboxylate Ethyl 5-amino-1H-4-pyrazolecarboxylate ETHYL 5-AMINO-1H-PYRAZOLE-4-CARBOXYLATE Ethyl 3-amino-1H-pyrazole-4-carboxylate Ethyl 5-amino-1H-pyrazole-4-carboxylate 5-AMINO-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 5-Amino-1H-pyrazole-4-carboxylic acid ethyl ester 3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester 1H-Pyrazole-4-carboxylic acid, 5-amino-, ethyl ester 1H-Pyrazole-4-carboxylic acid, 3-amino-, ethyl ester
CAS	19750-02-8 1260243-04-6
EINECS	230-262-3
InChI	InChI=1/C6H9N3O2/c1-2-11-6(10)4-3-8-9-5(4)7/h3H,2H2,1H3,(H3,7,8,9)

3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C6H9N3O2
Molar Mass	155.15
Density	1.318g/cm³
Boling Point	349.2°C at 760 mmHg
Flash Point	165°C
Vapor Presure	4.79E-05mmHg at 25°C
Storage Condition	2-8 ℃, dark
Sensitive	Irritant
Refractive Index	1.584
MDL	MFCD00114562

3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester - Introduction

acid ethyl ester, chemical formula C7H8N2O2, is an organic compound. The following is a description of the relevant Properties, Uses, methods and safety information:

Nature:
-acid ethyl ester is a white crystal with a special smell.
-It is soluble in a variety of organic solvents at room temperature, such as ethanol, ether, chloroform, etc.
-The melting point of this compound is about 121-123°C.
-It is more stable under acidic conditions, but will degrade under alkaline conditions.

Use:
-or acid ethyl ester is commonly used as an amine group protecting reagent in organic synthesis.
-It can be combined by acid or nucleophile to form a temporary protecting group, Protect the amine group from reacting with other reagents, and increase the selectivity of organic synthesis.
-In addition, it can also be used to synthesize 3-aminopyrazole acyl compounds required for various studies.

Method:
-The preparation of acid ethyl ester is usually obtained by reacting 3-aminopyrazole with ethyl formate under alkaline conditions.
-Reaction Ethyl formate is added to the solution of 3-aminopyrazole, and a base is added to promote the reaction.
-After the reaction is completed, the target product is obtained through steps such as acidification and crystallization.

Safety Information:
-acid ethyl ester is irritating and corrosive.
-After contact with skin and eyes, rinse immediately with plenty of water and seek medical help.
-Good ventilation measures should be taken during operation to avoid inhalation and contact.
-Store away from high temperature, fire and oxidant.
-Please follow the chemical safety procedures for use.

Last Update：2024-04-10 22:29:15